佣兵天下小说硼酸被硝基取代生成硝基化合物反应示例-有机合成
硼酸被硝基取代生成硝基化合物反应示例-有机合成
芳基硼酸用 NH 4 NO 3 /(CF 3 CO) 2 O， NH 4 NO 3 / TMSCl 或 MNO 3 /TMSCl （M＝Ag辉子爷，Na石田萌美，K）处理异镇演员表 ，发生硼被硝基取代的反应迟帅的老婆 ，生成硝基化合物张殊凡 。前一个条件比较强，后两个条件相对温和，反应在室温下进行蔡乔恩 ，收率高，这是最近报导的一种方法小妹不要怕 ，应用面还不太广。
反应实例
To the mixture of silver nitrate (374 mg无限航路 , 2.2 mmol) in DCM (10 mL) was added TMSCl(238 mg, 2.2 mmol),章玉善 the mixture was stirred for 15 min温天淳 , followed by the addition of3-chlorophenylboronic acid (156 mg间谍迷城 , 1mmol). The resulting mixture was stirred at rt for 72h, then filtered, the filtrate was washed with NaHCO 3 solution佣兵天下小说 烈女镖客 , extracted with DCM. Thesolvent was removed under reduced pressure曹飞飞 , the residue was purified by columnchromatography to give the desired compound (140 mg, 90%). 、
Prakash, G. K. S; Panja稻叶千秋 , C; Mathew, T; Olah, G. A. Org. Lett海底猎人, 2004, 2205
本文非原创内容条子骇客 ，版权归原作者所有
芳基硼酸用 NH 4 NO 3 /(CF 3 CO) 2 O， NH 4 NO 3 / TMSCl 或 MNO 3 /TMSCl （M＝Ag辉子爷，Na石田萌美，K）处理异镇演员表 ，发生硼被硝基取代的反应迟帅的老婆 ，生成硝基化合物张殊凡 。前一个条件比较强，后两个条件相对温和，反应在室温下进行蔡乔恩 ，收率高，这是最近报导的一种方法小妹不要怕 ，应用面还不太广。
反应实例
To the mixture of silver nitrate (374 mg无限航路 , 2.2 mmol) in DCM (10 mL) was added TMSCl(238 mg, 2.2 mmol),章玉善 the mixture was stirred for 15 min温天淳 , followed by the addition of3-chlorophenylboronic acid (156 mg间谍迷城 , 1mmol). The resulting mixture was stirred at rt for 72h, then filtered, the filtrate was washed with NaHCO 3 solution佣兵天下小说 烈女镖客 , extracted with DCM. Thesolvent was removed under reduced pressure曹飞飞 , the residue was purified by columnchromatography to give the desired compound (140 mg, 90%). 、
Prakash, G. K. S; Panja稻叶千秋 , C; Mathew, T; Olah, G. A. Org. Lett海底猎人, 2004, 2205
本文非原创内容条子骇客 ，版权归原作者所有